Background:  The organic anion transporting polypeptide (OATP) family of proteins play a role in drug absorption, distribution and excretion. OATP proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. PGT, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or OATP2A1, is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, PGT is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding PGT maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Description: Rabbit polyclonal to SLCO2A1

Immunogen: KLH conjugated synthetic peptide derived from SLCO2A1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 70 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.