Background:  Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF740 (zinc finger protein 740) is a 193 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. One of several members of the Krüppel C2H2-type zinc-finger protein family, ZNF740 is thought to play a role in transcriptional regulation. The gene encoding ZNF740 maps to human chromosome 12, which houses over 1,100 genes and comprises approximately 4.5% of the human genome.

Description: Rabbit polyclonal to ZNF740

Immunogen: KLH conjugated synthetic peptide derived from ZNF740

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 22 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.