Background:  The acyl-CoA dehydrogenase (ACAD) family of enzymes are involved in the catabolism of fatty acids and amino acids and they provide a major source of energy for the heart and skeletal muscle. ACADL (acyl-Coenzyme A dehydrogenase, long chain), also known as LCAD or ACAD4, is a 430 amino acid protein that localizes to the mitochondrial matrix and belongs to the acyl-CoA dehydrogenase family. Existing as a homotetramer, ACADL uses FAD as a cofactor to catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acids. Defects in the gene encoding ACADL are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, which leads to non-ketotic hypoglycemia and hypotonia.

Description: Rabbit polyclonal to ACADL

Immunogen: KLH conjugated synthetic peptide derived from ACADL

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 48 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.