Background:  DEAD box proteins are putative RNA helicases, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as ribosome and spliceosome assembly, translation initiation and nuclear and mitochondrial splicing. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. Mutations in DDX3Y cause male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that it plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.

Description: Rabbit polyclonal to DDX3Y

Immunogen: KLH conjugated synthetic peptide derived from DDX3Y

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 73 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.