Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
Description: Rabbit polyclonal to GRK1
Immunogen: KLH conjugated synthetic peptide derived from GRK1
Specificity: ·Reacts with Human, Mouse, Chicken, Cow and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/200-500. Predicted Mol wt: 60 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.