Background:  The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is localized primarily in cardiac tissue and is involved in mediation of bradycardia and a decrease in cardiac contractility.

Description: Rabbit polyclonal to ChRM2

Immunogen: KLH conjugated synthetic peptide derived from ChRM2

Specificity:  ·Reacts with Human, Mouse, Pig, Cow, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/200-500. Predicted Mol wt: 52 kDa;

·Immunohistochemistry (Paraffin/Frozen tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/1000;

·Optimal working dilutions must be determined by the end user.