Background:  PRDM5 is a transcription factor of the PR-domain protein family, and contains a PR-domain at the -NH2 terminus followed by 16 zinc finger motifs. It has been found to have a role in cell differentiation and tumorigenesis. A recombinant adenovirus expressing PRDM5 caused G2/M arrest and apoptosis upon infection of tumor cells. PRMD5 has been found to be silenced in breast, ovarian and lung cancers. The inactivation of PRDM5 may play a role in carcinogenesis.

Description: Rabbit polyclonal to PRDM5

Immunogen: KLH conjugated synthetic peptide derived from PRDM5

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 73 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-200;

·Immunocytochemistry: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.