Background:  KLHL26, also known as kelch-like protein 26, is a 615 amino acid protein similar to similar to the Drosophila kelch protein. KLHL26 contains one BACK (BTB/Kelch associated) domain, which may indicate a role in substrate orientation in E3 ligase complexes. KLHL26 also contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.

Description: Rabbit polyclonal to KLHL26

Immunogen: KLH conjugated synthetic peptide derived from KLHL26

Specificity:  ·Reacts with Human, Mouse, Chicken and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 68 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-200;

·Immunocytochemistry: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.