Background:  Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L19 is a 196 amino acid protein that is a component of the 60S subunit. Localized to the cytoplasm, Ribosomal Protein L19 belongs to the L19e family of ribosomal proteins and functions in protein synthesis. The expression of Ribosomal Protein L19 is upregulated in breast cancers and its overexpression is used as a prognostic marker for prostate cancer. Like most ribosomal proteins, Ribosomal Protein L19 exists as multiple processed pseudogenes that are scattered throughout the genome.

Description: Rabbit polyclonal to RPL19

Immunogen: KLH conjugated synthetic peptide derived from RPL19

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 23 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-200;

·Immunocytochemistry: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.