Background:  HATH6, also known as atonal homolog 8 (ATOH8), is a 321 amino acid putative transcription factor. Localized to the nucleus, HATH-6 is expressed in kidney, lung, liver, pancreas, heart and the endothelium of umbilical vessels. HATH-6 is thought to participate in podocyte development in the kidney and may be involved in specification and differentiation of brain neuronal cell lineages. As a transcription factor, HATH-6 contains one basic helix-loop-helix (bHLH) domain. In order to efficiently bind to DNA, HATH-6 must be bound to another bHLH domain containing protein. HATH-6 exists as two isoforms produced by alternative splicing.

Description: Rabbit polyclonal to HATH6

Immunogen: KLH conjugated synthetic peptide derived from HATH6

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 35 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.