Background:  Interferon-related developmental regulator-1 (IFRD1) gene is a human homolog of the rat PC4 gene initially isolated as a nerve growth factor-inducible sequence in PC12 cells. PC4 is present at high levels along the neural tube of early rat embryos. Expression of PC4 in the myoblast C2C12 cell line decreases within 6 hours from the onset of differentiation, attains a minimum after 12 hours, and returns to basal level within 36 hours; the transient down-regulation of PC4 expression can be prevented by transforming growth factor beta, a molecule which inhibits the differentiation of muscle.

Description: Rabbit polyclonal to IFRD1

Immunogen: KLH conjugated synthetic peptide derived from IFRD1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 50 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.