Background: BEND3(BEN domain-conaining protein 3) is an 828 amino acid protein that contains 4 BEN domains. BEND3 is considered a complete proteome as well as a phosphoprotein. BEN domain mediates protein-DNA and protein-protein interactions during chromatin organization and transcription. The BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND3 gene maps to human chromosome 6q21. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated，predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson’s disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6.

Description: Rabbit polyclonal to BEND3

Immunogen: KLH conjugated synthetic peptide derived from BEND3

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 94 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.