Background: Endocannaboids such as arachidonoyl ethanolamide and 2-arachidonoyl glycerol function as short range modulators of cell and synaptic activity. Monoacylglycerol lipase hydrolyzes 2-arachidonoyl glycerol which terminates it's biological actions. Monoacylglycerol lipase also works consecutively with hormone sensitive lipase to mobilize fatty acids from triglyceride stores of adipocytes. Monoacylglycerol lipase is expressed in kidney, spleen, heart, liver, testis, stomach, brain and lung tissue, and adrenal gland. It is most abundantly expressed in skeletal muscle and adipose tissue.
Description: Rabbit polyclonal to Monoacylglycerol Lipase
Immunogen: KLH conjugated synthetic peptide derived from Monoacylglycerol Lipase
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 33 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.