Background:  Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. Metallothionein proteins may play a central role in the regulation of cell growth, differentiation and are involved in spermatogenesis. Tesmin (testis-specific metallothionein-like protein), also designated MTLT, CXCDC2 or MTL5, is a 508 amino acid nuclear and cytoplasmic protein that is specifically expressed in spermatocytes. A member of the lin-54 family, Tesmin may be involved in multiple stages of spermatogenesis and spermiogenesis, possibly during sperm maturation and/or morphogenesis. Tesmin contains two CXC domains and exists as three alternatively spliced isoforms. Tesmin is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

Description: Rabbit polyclonal to MLT5

Immunogen: KLH conjugated synthetic peptide derived from MLT5

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 58 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.