Background:  CD303/CLEC4C/BDCA-2 is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells and may act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Two transcript variants encoding distinct isoforms have been identified.

Description: Rabbit polyclonal to CD303

Immunogen: KLH conjugated synthetic peptide derived from CD303

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 25 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.